{"id":8677,"date":"2021-03-15T12:48:00","date_gmt":"2021-03-15T12:48:00","guid":{"rendered":"https:\/\/hipradermic.com\/inyectores-sin-aguja-para-la-vacunacion-intradermica-porcina-la-importancia-de-la-precision\/"},"modified":"2021-07-13T10:14:05","modified_gmt":"2021-07-13T10:14:05","slug":"inyectores-sin-aguja-para-la-vacunacion-intradermica-porcina-la-importancia-de-la-precision","status":"publish","type":"post","link":"https:\/\/hipradermic.com\/es\/inyectores-sin-aguja-para-la-vacunacion-intradermica-porcina-la-importancia-de-la-precision\/","title":{"rendered":"Inyectores sin aguja para la vacunaci\u00f3n intrad\u00e9rmica porcina: la importancia de la precisi\u00f3n"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"8677\" class=\"elementor elementor-8677 elementor-8269\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1800acbe elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1800acbe\" data-element_type=\"section\" data-e-type=\"section\" data-settings=\"{&quot;jet_parallax_layout_list&quot;:[{&quot;jet_parallax_layout_image&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;_id&quot;:&quot;eb6708b&quot;,&quot;jet_parallax_layout_image_tablet&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_image_mobile&quot;:{&quot;url&quot;:&quot;&quot;,&quot;id&quot;:&quot;&quot;,&quot;size&quot;:&quot;&quot;},&quot;jet_parallax_layout_speed&quot;:{&quot;unit&quot;:&quot;%&quot;,&quot;size&quot;:50,&quot;sizes&quot;:[]},&quot;jet_parallax_layout_type&quot;:&quot;scroll&quot;,&quot;jet_parallax_layout_direction&quot;:null,&quot;jet_parallax_layout_fx_direction&quot;:null,&quot;jet_parallax_layout_z_index&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x&quot;:50,&quot;jet_parallax_layout_bg_x_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_x_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y&quot;:50,&quot;jet_parallax_layout_bg_y_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_y_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size&quot;:&quot;auto&quot;,&quot;jet_parallax_layout_bg_size_tablet&quot;:&quot;&quot;,&quot;jet_parallax_layout_bg_size_mobile&quot;:&quot;&quot;,&quot;jet_parallax_layout_animation_prop&quot;:&quot;transform&quot;,&quot;jet_parallax_layout_on&quot;:[&quot;desktop&quot;,&quot;tablet&quot;]}]}\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-590579c1\" data-id=\"590579c1\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-25d9e028 elementor-widget elementor-widget-text-editor\" data-id=\"25d9e028\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t<blockquote>\n<p><strong>Aunque existen muchos sistemas de administraci\u00f3n que facilitan la aplicaci\u00f3n intrad\u00e9rmica de las vacunas (Kis et al., 2012), en cerdos, los inyectores sin aguja son, sin duda, los m\u00e1s utilizados (Figura&nbsp;1). La aplicaci\u00f3n intrad\u00e9rmica de las vacunas con un inyector sin aguja implica la administraci\u00f3n de un peque\u00f1o volumen de vacuna de aproximadamente 0,2&nbsp;ml.<\/strong><\/p>\n<\/blockquote>\n<p style=\"text-align: center;\"><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter wp-image-8311\" src=\"https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-needle-free-vaccination-device.jpg\" alt=\"\" width=\"550\" height=\"287\" srcset=\"https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-needle-free-vaccination-device.jpg 768w, https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-needle-free-vaccination-device-300x157.jpg 300w, https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-needle-free-vaccination-device-600x313.jpg 600w\" sizes=\"(max-width: 550px) 100vw, 550px\" \/><\/p>\n<h6 style=\"text-align: center;\">Figura&nbsp;1. Hipradermic\u00ae 3.0, dispositivo sin aguja para la aplicaci\u00f3n intrad\u00e9rmica de vacunas en producci\u00f3n porcina.<\/h6>\n<p style=\"text-align: center;\"><em>La aplicaci\u00f3n intrad\u00e9rmica de vacunas con un inyector sin aguja ofrece muchos beneficios, especialmente en lo que respecta a la ausencia de utilizaci\u00f3n de agujas, tales como: la eliminaci\u00f3n de la posibilidad de agujas rotas y de da\u00f1os en las canales, o el riesgo de lesiones accidentales por pinchazo de aguja para los empleados. <\/em><\/p>\n<p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\">Tambi\u00e9n<strong> reducen el riesgo de propagaci\u00f3n de enfermedades vir\u00e9micas<\/strong>, tales como el <strong>vPRRS,<\/strong> que se produce cuando se reutiliza la misma aguja o la misma jeringa en varios animales.<\/p>\n<p>Adem\u00e1s, <strong>la vacunaci\u00f3n sin aguja<\/strong> mediante inyecci\u00f3n intrad\u00e9rmica ofrece muchas ventajas en comparaci\u00f3n con otros tipos de vacunaci\u00f3n; <strong>es una t\u00e9cnica menos invasiva y produce menos ansiedad y dolor al animal.<\/strong><\/p><p><strong><br><\/strong><\/p>\n<p style=\"text-align: center;\"><em>Se ha demostrado que reducir el dolor y el estr\u00e9s de los cerdos en producci\u00f3n incrementa su bienestar general y su capacidad de crecimiento (Mart\u00ednez-Mir\u00f3 et al., 2016).<\/em><\/p><p style=\"text-align: center;\"><em><br><\/em><\/p>\n<h2>Mecanismo sin aguja<\/h2>\n<p>El mecanismo de los inyectores sin aguja se basa en el principio de impulsar con fuerza un l\u00edquido a trav\u00e9s de un peque\u00f1o orificio, de forma que se genera una corriente de alta presi\u00f3n para penetrar en la piel a gran velocidad (aproximadamente 100&nbsp;m\/s).<\/p>\n<p><strong>El impacto del l\u00edquido sobre la piel genera un orificio a trav\u00e9s del cual se introduce el l\u00edquido en el tejido sin ayuda de una aguja.<\/strong><\/p>\n<p>La administraci\u00f3n de una formulaci\u00f3n l\u00edquida mediante un inyector puede dividirse en tres etapas generales, que necesitan un tiempo total <strong>inferior a 0,3&nbsp;segundos<\/strong>:<\/p>\n<p>En la primera, se observa una <strong>fase de presi\u00f3n m\u00e1xima<\/strong>, una presi\u00f3n \u00f3ptima utilizada para <strong>penetrar en la piel<\/strong> (Figura 2. Perfil de presi\u00f3n: A).<\/p>\n<p>A esto le sigue la <strong>fase de dispersi\u00f3n<\/strong>. B), que proporciona una <strong>dispersi\u00f3n amplia del l\u00edquido en el tejido<\/strong> ya que fuerza una v\u00eda a trav\u00e9s de las regiones de baja resistencia, lo que da lugar a una distribuci\u00f3n amplia de la vacuna en forma de tela de ara\u00f1a.<\/p>\n<p>Se cree que esta amplia dispersi\u00f3n de la vacuna aumenta la exposici\u00f3n del ant\u00edgeno a las c\u00e9lulas presentadoras de ant\u00edgeno, lo que da lugar a una mayor respuesta inmunitaria.<\/p>\n<p>Por \u00faltimo, se produce la fase de reducci\u00f3n (Figura 2. Perfil de presi\u00f3n: C).<\/p><p><br><\/p>\n<p style=\"text-align: center;\"><em>El perfil de presi\u00f3n uniforme de un inyector sin aguja garantiza un proceso homog\u00e9neo en el que se vacuna cada animal a la profundidad del tejido seleccionado (Chase et al., 2008).<\/em><\/p>\n<p><img decoding=\"async\" class=\"aligncenter wp-image-8383 size-full\" src=\"https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-needle-free-vaccination-swine.png\" alt=\"\" width=\"1024\" height=\"535\" srcset=\"https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-needle-free-vaccination-swine.png 1024w, https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-needle-free-vaccination-swine-300x157.png 300w, https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-needle-free-vaccination-swine-768x401.png 768w, https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-needle-free-vaccination-swine-600x313.png 600w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/p>\n<h6 style=\"text-align: center;\">Figura 2. Representaci\u00f3n de las tres fases de presi\u00f3n distintas de un dispositivo sin aguja durante la administraci\u00f3n intrad\u00e9rmica de una vacuna en la piel de un cerdo.<\/h6>\n<h2>Vacunaci\u00f3n: aplicaci\u00f3n intrad\u00e9rmica<\/h2>\n<p>En el caso de la aplicaci\u00f3n intrad\u00e9rmica de vacunas, es importante ajustar de forma adecuada la presi\u00f3n y la fuerza del dispositivo sin aguja para garantizar el dep\u00f3sito de la vacuna espec\u00edficamente en la capa de la dermis (Figura&nbsp;3).<\/p>\n<p style=\"text-align: center;\"><img decoding=\"async\" class=\"aligncenter wp-image-8345 size-full\" src=\"https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-transdermal.jpg\" alt=\"\" width=\"933\" height=\"285\" srcset=\"https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-transdermal.jpg 933w, https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-transdermal-300x92.jpg 300w, https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-transdermal-768x235.jpg 768w, https:\/\/hipradermic.com\/wp-content\/uploads\/2021\/05\/intradermal-transdermal-600x183.jpg 600w\" sizes=\"(max-width: 933px) 100vw, 933px\" \/><\/p>\n<h6 style=\"text-align: center;\">Figura&nbsp;3. Distribuci\u00f3n intrad\u00e9rmica y transd\u00e9rmica de una vacuna espec\u00edfica en la piel de un cerdo con distintos dispositivos inyectores sin aguja, mostradas mediante rayos&nbsp;X. Administraci\u00f3n de la vacuna en la regi\u00f3n posterior del cerdo (A) y en la regi\u00f3n del cuello del cerdo (B). Estudio interno.<\/h6>\n<p><strong>Cuando se deposita una vacuna intrad\u00e9rmica fuera de la capa de dermis, no puede garantizarse la eficacia esperada. <\/strong><\/p>\n<p><strong>Por lo tanto, es importante destacar que no todos los inyectores sin aguja disponibles en el mercado son capaces de tener la misma precisi\u00f3n para garantizar la administraci\u00f3n satisfactoria de la vacuna en la capa de dermis.<\/strong><\/p>\n<p style=\"text-align: left;\"><br><\/p><p style=\"text-align: left;\">Referencias bibliogr\u00e1ficas:<\/p>\n<h5><em>Chase C.L., et al (2008). Swine Health Prod, 254-260<br>Kris E.E, et al. (2012). Vacuna, 30(3):523-38<br>Martinez-Miro S., et al. (2016). Vet Res., 12: 171<br>Taberner A., et al. (2012). Medical Engineering &amp; Physic 34:1228-1235<br><\/em><\/h5>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>La vacunaci\u00f3n sin aguja mediante inyecci\u00f3n intrad\u00e9rmica ofrece muchas ventajas en comparaci\u00f3n con otros tipos de vacunaci\u00f3n; es una t\u00e9cnica menos invasiva y produce menos ansiedad y dolor al animal.  <\/p>\n","protected":false},"author":9,"featured_media":7997,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jet_sm_ready_style":"","_jet_sm_style":"","_jet_sm_controls_values":"","_jet_sm_fonts_collection":"","_jet_sm_fonts_links":"","footnotes":""},"categories":[19],"tags":[41,40,42],"class_list":["post-8677","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dispositivo-intradermico-sin-aguja","tag-diseno","tag-empresa","tag-moda"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.5 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Inyectores sin aguja para la vacunaci\u00f3n intrad\u00e9rmica porcina: la importancia de la precisi\u00f3n | Hipradermic<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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